Losartan Ophthalmic Solution

A NOVEL OFF-LABEL USE FOR A COMMON MEDICATION

What is Losartan for Ophthalmic Use?

Losartan, an angiotensin-converting enzyme (ACE) II receptor antagonist, is commonly taken orally to treat high blood pressure. It has also been linked to inhibition of transforming growth factor (TGF) beta signaling. Refractive surgeon Steven E. Wilson, MD, Director of Corneal Research at Cleveland Clinic Cole Eye Institute, developed and studied an off-label treatment utilizing topical losartan. The intent was to target corneal myofibroblasts, which is the main cause behind persistent corneal scarring after infection, injury, or refractive surgery. Outcomes of the studies have been promising and leading to succesful off-label use around the world.

Wilson, S. E. (2023). Topical losartan: Practical guidance for clinical trials in the prevention and treatment of corneal scarring fibrosis and other eye diseases and disorders. Journal of Ocular Pharmacology and Therapeutics, 39(3), 191–206.

Our Approach

Upon a receipt of a prescription from your physician, a friendly team member will welcome you to our family and assist you through the process. The eye drops are checked, packaged, and shipped to your doorstep. Our knowledgeable pharmacist will be your advocate and resource throughout the duration your treatment.

Formulas and/or material listed are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment. Every patient is unique, and formulas should be adjusted to meet their individual needs.

No compounded medications are reviewed by the FDA for safety or efficacy.